Question & Answer: Transmembrane proteins are embedded in cell membranes. If one transmembrane protein is…..

2. Transmembrane proteins are embedded in cell membranes. If one transmembrane protein is pulled away from the cell membrane using a magnetic force microscope (reading material: pp. 18 of the text book), and the force required to extract this protein is: IS: where x is the distance between the protein and membrane. The protein is pulled from the fully embedded state (x-0 2.1 What is the work needed to extract this transmembrane protein? 2.2 What would be the work (in Joule) needed to extract 1 mole of such transmembrane protein? ) to fully unbinded state (x 5 nm)

Transmembrane proteins are embedded in cell membranes. If one transmembrane protein is pulled away from the cell membrane using a magnetic force microscope (reading material: pp. 18 of the text book), and the force required to extract this protein is: (f | pN) = 15 (x/nm) + (x/nm)^2 where x is the distance between the protein and membrane. The protein is pulled from the fully embedded state (x_1 = 0) to fully unbinded state (x_2 = 5 nm) What is the work needed to extract this transmembrane protein? What would be the work (in Joule) needed to extract 1 mole of such transmembrane protein?

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