Question & Answer: Cancer of the prostate is the second leading cause of cancer deaths among American males,…..

Cancer of the prostate is the second leading cause of cancer deaths among American males, exceeded only by lung cancer. One treatment of prostate cancer is based on the fact that testosterone and androsterone (both androgens) enhance the proliferation of prostate tumors. The drug flutamide (an antiandrogen) reduces the level of androgens in target tissues and is currently used to prevent and treat prostate cancer. Propose a synthesis of flutamide from (trifluoromethyl)benzene From the table of reagents, select the components necessary to synthesize the given molecule and enter their letters, in the order that they are to be used without commas between, in the box, i.e. ‘hiacc’ If a reaction is to be used more than once, enter its letter multiple times as necessary Reagents Available CH_3CH=CH_2, H_3PO_4 acetyl chloride, AICl_3 HNO_3/H_2SO_4 2-methylpropanoyl chloride, AICl_3 H_2, Pd/C f. BH_3/THF H_2NNH_2, OH^-, H_2O OH^? CH_3l H_2CrO_4 Br_2, FeBr_3 SOCI_2 Cl_2, FeCl_3 Cl_2, Delta propanoyl chloride, AlCl_3 Br_2, H^+ t-butylamine